Microwave assisted organic synthesis

 Microwave assisted organic synthesis 

microwave assisted Eco friendly organic  synthesis trend with many applications in synthesizing organic materials. organic reaction under the microwave irradiation have many advantages compiard to conventional reactions need varry high  temperature. Microwave assisted reactions are cleaner last only few minutes have high yield and produce minimum waste (Lindstrom and wathey  2001)

Microwave assisted synthesis can be solvent

assisted or solvent free methods

AlCl3 has been used as catalyst for microwave enhanced and solvent free green protocol for production of dihydropyrimidine-2-(1H)-ones (suresh and sandhu 2010)

Beckman rearrangement of oximes in the solid state with microwave irradiation gave quantitative yields of the product without use of catalysts.

   Ultrasound assisted organic synthesis is another green methodology wich applied in many organic synthetic routes with grate advantages for high efficiency low energy requirements sono Chemical processes are most widely developed for heterogeneous reactions 

   B-Amino-a, B- unsaturated Esters were produced by sono-Chemical  blaise reaction of nitriles,  zenic powder, zinc oxide and ethyl bromo acetate in THF in commercial ultra sonic cleaning bath (ylee and cheng 1997)

It is need to design chemicals and there forms to minimize the chemical accidents including explosion , fires and releases to environment.Early manufacturers of gold atom nano particles used diborane (highly toxic and bursts into flames near room temperature) and cancer causing benzene. But now diborane is replaced by NaBH4 wich is environmentally benign. Nono science and nano technology is another important contribution to green chemistry 

    Thus there is a need to develop the method of green synthes wich will minimize the use of chemiclas and there will br growth towardes sustainable development