Cannizzaro Reacton

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Cannizzaro Reacton

 Cannizzaro reaction

Cannizzaro reaction

This redox disproportionation of non-enolizable aldehydes to carboxylic acids and alcohols is conducted in concentration base.a-Keto aldehydes give the product of an intramolecular disproportionation in excellent yeilds. 

Mechanism of cannizaro Reaction 

Macanisim of Cannizzaro reaction

An interesting variant,  the crossed cannizzaro Reaction , uses formaldehyde as reducing agent :

Cannizzaro reaction

All the presnt time,  various oxidizing and reducing agents can be used to carry out such conversation (with higher yeilds) , so that today the Cannizzaro reaction has limited synthetic utility except for the above-mentioned conversation of a-Keto aldehydes. 

       The canizzaro reaction should be kept in mind as a source of potential side products when aldehydes are treated under basic conditions.

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